Novel Laser based technique for Tissue
Novel Laser based technique for Tissue dissectionfor hard tissue and implants histopathological evaluation: At Patho-Logica, we pride ourselves on redefining standards in tissue and material analysis. With our novel Tissue Surgeon method, we’re setting a new benchmark in precision, efficiency, and reliability for researchers and clinicians worldwide for hard tissues and implant histopathology. This state-of-the-art […]
Calibration of IHC for Covid-19 virus
Calibration of IHC for Covid-19 virus in Golden Syrian Hamsters Dr. Emmanuel loeb, Dr. Zohar Gavish, Patho-Logica Ltd. Results: The objective was to detect a specific IHC signal in relevant structures of the lung in paraffin sections (4 microns thick). Two animal groups were examined: covid-19 intranasal infected hamsters and a Naïve group. Primary serum […]
Digitalization of Pathology
How Artificial Intelligence (AI) and Deep Learning (DL) processes are shaping and influencing the work of the experimental pathologist. Introduction Technology developments have changed and will continue to change many fields. When it comes to science and precise data, technology developments are becoming a real challenge for professionals such as pathologists who are used […]
Treatment in Peripheral Nerve Injury
Photobiomodulation Triple Treatment in Peripheral Nerve Injury: Nerve and Muscle Response Mira M. Mandelbaum-Livnat, PhD,1 Mara Almog, PhD,1 Moshe Nissan, PhD,1 Emmanuel Loeb, DVM,2 Yuval Shapira, MD,1 and Shimon Rochkind, MD, PhD1 Abstract Background: Muscle preservation or decrease in muscle degeneration and progressive atrophy are major challenges in patients with severe peripheral nerve injury (PNI). […]
Treatment of Experimental Actinic Keratoses
A Hexokinase 2 Modulator for Field-Directed Treatment of Experimental Actinic Keratoses Vered Behar, Hadas Pahima, Adi Kozminsky-Atias, Nir Arbel, Emmanuel Loeb, Max Herzberg and Oren M. Becker Overexpression of hexokinase 2, and its binding to VDAC1 on the outer mitochondrial membrane of cancer cells, is key to their metabolic reprogramming to aerobic glycolysis, which enables them […]
The pros and cons of animal experiments
The pros and cons of animal experiments; an essay on ethical issues Author: Emmanuel Loeb As an experimental pathologist, I deal on a daily basis with tissue samples that were harvested during a controlled animal experiment, performed as part of the development process of new drugs and devices. In my opinion, a proper ethical approach […]
The Usage of Animal Models
The Usage of Animal Models for Pre-Clinical Trials: a pathological, comparative approach Author: Emmanuel Loeb. The utilazation of animal models offers the scientist a great opportunity to examine his developed product (drug or medical device) on a whole body system prior to the human trials. The animal model intends to mimic in a group of […]
Technocratic Scientific Empire
Technocratic Scientific Empire – the good, the bad, and the man that could not dream Author: Emmanuel Loeb We all live in a technocratic capitalistic world that demands innovation and advanced developments to improve health and quality of life, as well as to increase income and prosperity. If we compare the scientific work and articles […]
Utilizing Patients-Derived Xenografts
Utilizing Patients-Derived Xenografts and Histological Assessment for Personized Medicine in Oncology Author: Emmanuel Loeb Globally, 8.2 million people die each year from cancer, an estimated 13% of all deaths worldwide. There is a 70% increase in the expected new cases of cancer over the next 2 decades. According to the W.H.O, more than 100 cancer […]